Predictive modeling and experimental implementation of organic acids in stream recovery by reactive extraction in membrane contactors

• Substantial reduction of acid accumulation with the coupled process. Great viscosity variations due to transfer. Viscosity changes successfully taken into account describe kinetics. Model-based generalization for process guidelines. Membrane-based reactive extraction as an in situ product recovery technique is a promising strategy intensification, particular case bioproduction organic acids. Reactive allows high selectivity targeted and microporous membrane keeps biocatalysts aqueous broth while implementing large liquid–liquid surface area ensuring dispersion-free contact, without problems emulsion formation. This paper deals specifically biobased 3-hydroxypropionic using tri- n -octylamine -decanol. In order maintain effective driving force 3-HP transfer phase, this latter was continuously regenerated by recovering back-extraction giving complete pertraction A mass model developed. It based on boundary layer theory takes chemical physical equilibria complexation/dissociation partitioning, species diffusion pores phase. highly depends concentration, increasing up 50% when concentration reaches 28 g.L -1 . Thus, it possible predict different experimental results R 2 ? 0.99, totally neglecting kinetics interfacial resistance both steps. The prediction (1) fixed initial concentrations (2) gradual feed (mimicking bioconversion) transient steady states (globally also called pertraction). Model analysis mechanisms led construction nomogram stationary typical production rate, enabling example rapid phase selection or sizing.